Publikationen der Core Facility
Freitag T, Kaps P, Ramtke J, Bertels S, Zunke E, Schneider B, Becker A-S, Koczan D, Dubinski D, Freiman TM, Wittig F, Hinz B, Westhoff M-A, Strobel H, Meiners F, Wolter D, Engel N, Troschke-Meurer S, Bergmann-Ewert W, Staehlke S, Wolff A, Gessler F, Junghanss C, Maletzki C. 2024. Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma. NPJ Precis Oncol 8:156. doi:10.1038/s41698-024-00653-3.
Kayser A, Wolff A, Berlin P, Duehring L, Henze L, Mundkowski R, Bergmann W, Müller-Hilke B, Wagner C, Huehns M, Oehmcke-Hecht S, Maletzki C. 2024. Selective but not pan-CDK inhibition abrogates 5-FU-driven tissue factor upregulation in colon cancer. Sci Rep 14:10582. doi:10.1038/s41598-024-61076-5.
Mai F, Bergmann W, Reisinger EC, Müller-Hilke B. 2024. The varying extent of humoral and cellular immune responses to either vector- or RNA-based SARS-CoV-2 vaccines persists for at least 18 months and is independent of infection. J Virol 98:e0191223. doi:10.1128/jvi.01912-23.
Mai F, Kordt M, Bergmann-Ewert W, Reisinger EC, Müller-Hilke B. 2024. NVX-CoV2373 induces humoral and cellular immune responses that are functionally comparable to vector and mRNA-based vaccines. Front Immunol 15:1359475. doi:10.3389/fimmu.2024.1359475.
Wolff A, Krone P, Maennicke J, Henne J, Oehmcke-Hecht S, Redwanz C, Bergmann-Ewert W, Junghanss C, Henze L, Maletzki C. 2024. Prophylaxis with abemaciclib delays tumorigenesis in dMMR mice by altering immune responses and reducing immunosuppressive extracellular vesicle secretion. Transl Oncol 47:102053. doi:10.1016/j.tranon.2024.102053.
Bischofsberger M, Reinholdt C, Dannenhaus TA, Aleith J, Bergmann-Ewert W, Müller-Hilke B, Löbermann M, Reisinger EC, Sombetzki M. 2023. Individually or as a Team-The Immunological Milieu in the Lung Caused by Migrating Single-Sex or Mixed-Sex Larvae of Schistosoma mansoni. Pathogens 12. doi:10.3390/pathogens12121432.
Krone P, Wolff A, Teichmann J, Maennicke J, Henne J, Engster L, Salewski I, Bergmann W, Junghanss C, Maletzki C. 2023. Short-term immune-checkpoint inhibition partially rescues perturbed bone marrow hematopoiesis in mismatch-repair deficient tumors. Oncoimmunology 12:2230669. doi:10.1080/2162402X.2023.2230669.
Linke C, Freitag T, Riess C, Scheffler JV, Del Moral K, Schoenwaelder N, Fiedler T, Fiebig A, Kaps P, Dubinski D, Schneider B, Bergmann W, Classen CF, Maletzki C. 2023. The addition of arginine deiminase potentiates Mithramycin A-induced cell death in patient-derived glioblastoma cells via ATF4 and cytochrome C. Cancer Cell Int 23:38. doi:10.1186/s12935-023-02873-2.
Lorenz P, Steinbeck F, Mai F, Reisinger EC, Müller-Hilke B. 2023. A linear B-cell epitope close to the furin cleavage site within the S1 domain of SARS-CoV-2 Spike protein discriminates the humoral immune response of nucleic acid- and protein-based vaccine cohorts. Front Immunol 14:1192395. doi:10.3389/fimmu.2023.1192395.
Maletzki C, Freiin Grote V, Kalle F, Kleitke T, Zimpfer A, Becker A-S, Bergmann-Ewert W, Jonitz-Heincke A, Bader R, Vollmar B, Hackenberg S, Scherzad A, Mlynski R, Strüder D. 2023. Establishing safe high hydrostatic pressure devitalization thresholds for autologous head and neck cancer vaccination and reconstruction. Cell Death Discov 9:390. doi:10.1038/s41420-023-01671-z.
Revskij D, Runst J, Umstätter C, Ehlers L, Rohde S, Zechner D, Bastian M, Müller-Hilke B, Fuellen G, Henze L, Murua Escobar H, Junghanss C, Kowald A, Walter U, Köhling R, Wolkenhauer O, Jaster R. 2023. Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice. Hepatobiliary Pancreat Dis Int 22:190–199. doi:10.1016/j.hbpd.2022.12.003.
Vasudevan P, Wolfien M, Lemcke H, Lang CI, Skorska A, Gaebel R, Galow A-M, Koczan D, Lindner T, Bergmann W, Mueller-Hilke B, Vollmar B, Krause BJ, Wolkenhauer O, Steinhoff G, David R. 2023. CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation. Genome Med 15:61. doi:10.1186/s13073-023-01213-3.
Aleith J, Brendel M, Weipert E, Müller M, Schultz D, Ko-Infekt SG, Müller-Hilke B. 2022. Influenza A Virus Exacerbates Group A Streptococcus Infection and Thwarts Anti-Bacterial Inflammatory Responses in Murine Macrophages. Pathogens 11. doi:10.3390/pathogens11111320.
Mai F, Volzke J, Reisinger EC, Müller-Hilke B. 2022. Vaccine-Induced T-Cell and Antibody Responses at 12 Months after Full Vaccination Differ with Respect to Omicron Recognition. Vaccines (Basel) 10. doi:10.3390/vaccines10091563.
Müller M, Volzke J, Subin B, Müller S, Sombetzki M, Reisinger EC, Müller-Hilke B. 2022. Single-dose SARS-CoV-2 vaccinations with either BNT162b2 or AZD1222 induce disparate Th1 responses and IgA production. BMC Med 20:29. doi:10.1186/s12916-022-02240-4.
Müller M, Volzke J, Subin B, Schmidt CJ, Geerdes-Fenge H, Reisinger EC, Müller-Hilke B. 2022. Distinguishing Incubation and Acute Disease Stages of Mild-to-Moderate COVID-19. Viruses 14. doi:10.3390/v14020203.
Müller-Hilke B, Mai F, Müller M, Volzke J, Reisinger EC. 2022. Higher SARS-CoV-2 Spike Binding Antibody Levels and Neutralization Capacity 6 Months after Heterologous Vaccination with AZD1222 and BNT162b2. Vaccines (Basel) 10. doi:10.3390/vaccines10020322.
Oehmcke-Hecht S, Berlin P, Müller-Hilke B, Kreikemeyer B, Vasudevan P, Henze L, Khaimov V, Vollmar B, David R, Maletzki C. 2022. The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer. Biomed Pharmacother 145:112429. doi:10.1016/j.biopha.2021.112429.
Kaddatz H, Joost S, Nedelcu J, Chrzanowski U, Schmitz C, Gingele S, Gudi V, Stangel M, Zhan J, Santrau E, Greiner T, Frenz J, Müller-Hilke B, Müller M, Amor S, van der Valk P, Kipp M. 2021. Cuprizone-induced demyelination triggers a CD8-pronounced T cell recruitment. Glia 69:925–942. doi:10.1002/glia.23937.
Schoenwaelder N, Salewski I, Engel N, Krause M, Schneider B, Müller M, Riess C, Lemcke H, Skorska A, Grosse-Thie C, Junghanss C, Maletzki C. 2021. The Individual Effects of Cyclin-Dependent Kinase Inhibitors on Head and Neck Cancer Cells-A Systematic Analysis. Cancers (Basel) 13. doi:10.3390/cancers13102396.
Volzke J, Müller-Hilke B. 2021. Degenerative Joint Damage Is Not a Risk Factor for Streptococcal Sepsis and Septic Arthritis in Mice. Life (Basel) 11. doi:10.3390/life11080794.
Boeckmann L, Schäfer M, Bernhardt T, Semmler ML, Jung O, Ojak G, Fischer T, Peters K, Nebe B, Müller-Hilke B, Seebauer C, Bekeschus S, Emmert S. 2020. Cold Atmospheric Pressure Plasma in Wound Healing and Cancer Treatment. Applied Sciences 10:6898. doi:10.3390/app10196898.
Buschhart A-L, Bolten L, Volzke J, Ekat K, Kneitz S, Mikkat S, Kreikemeyer B, Müller-Hilke B. 2020. Periodontal pathogens alter the synovial proteome. Periodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome in mice. PLoS One 15:e0242868. doi:10.1371/journal.pone.0242868.
Loeffler H, Jonitz-Heincke A, Peters K, Mueller-Hilke B, Fiedler T, Bader R, Klinder A. 2020. Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions. Materials (Basel) 13. doi:10.3390/ma13051150.
Schmidt CJ, Wenndorf K, Ebbers M, Volzke J, Müller M, Strübing J, Kriebel K, Kneitz S, Kreikemeyer B, Müller-Hilke B. 2020. Infection With Clostridioides difficile Attenuated Collagen-Induced Arthritis in Mice and Involved Mesenteric Treg and Th2 Polarization. Front Immunol 11:571049. doi:10.3389/fimmu.2020.571049.
Schoenwaelder N, Salewski I, Engel N, Krause M, Schneider B, Müller M, Riess C, Lemcke H, Skorska A, Grosse-Thie C, Junghanss C, Maletzki C. 2021. The Individual Effects of Cyclin-Dependent Kinase Inhibitors on Head and Neck Cancer Cells-A Systematic Analysis. Cancers (Basel) 13. doi:10.3390/cancers13102396.
Schultz D, Surabhi S, Stelling N, Rothe M, Group KoInfekt Study, Methling K, Hammerschmidt S, Siemens N, Lalk M. 2020. 16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens. Metabolites 10. doi:10.3390/metabo10030113.
Volzke J, Schultz D, Kordt M, Müller M, Bergmann W, Methling K, Kreikemeyer B, Müller-Hilke B. 2020. Inflammatory Joint Disease Is a Risk Factor for Streptococcal Sepsis and Septic Arthritis in Mice. Front Immunol 11:579475. doi:10.3389/fimmu.2020.579475.
Dohr D, Engelmann R, Müller-Hilke B. 2019. A novel method to efficiently isolate medullary thymic epithelial cells from murine thymi based on UEA-1 MicroBeads. J Immunol Methods 467:12–18. doi:10.1016/j.jim.2019.02.001.
Jonitz-Heincke A, Sellin M-L, Seyfarth A, Peters K, Mueller-Hilke B, Fiedler T, Bader R, Klinder A. 2019. Analysis of Cellular Activity Short-Term Exposure to Cobalt and Chromium Ions in Mature Human Osteoblasts. Materials (Basel) 12. doi:10.3390/ma12172771.
Lübcke PM, Ebbers MNB, Volzke J, Bull J, Kneitz S, Engelmann R, Lang H, Kreikemeyer B, Müller-Hilke B. 2019. Periodontal treatment prevents arthritis in mice and methotrexate ameliorates periodontal bone loss. Sci Rep 9:8128. doi:10.1038/s41598-019-44512-9.
Meyer J, Engelmann R, Kamp G, Peters K. 2019. Human adipocytes and CD34+ cells from the stromal vascular fraction of the same adipose tissue differ in their energy metabolic enzyme configuration. Exp Cell Res 380:47–54. doi:10.1016/j.yexcr.2019.04.018.
Neßlauer A-M, Gläser A, Gräler M, Engelmann R, Müller-Hilke B, Frank M, Burstein C, Rolfs A, Neidhardt J, Wree A, Witt M, Bräuer AU. 2019. A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1. Lipids Health Dis 18:146. doi:10.1186/s12944-019-1088-2.
Ebbers M, Lübcke PM, Volzke J, Kriebel K, Hieke C, Engelmann R, Lang H, Kreikemeyer B, Müller-Hilke B. 2018. Interplay between P. gingivalis, F. nucleatum and A. actinomycetemcomitans in murine alveolar bone loss, arthritis onset and progression. Sci Rep 8:15129. doi:10.1038/s41598-018-33129-z.
Engelmann R, Biemelt A, Johl A, Kuthning D, Müller-Hilke B. 2018. Reduced Numbers of Mature Medullary Thymic Epithelial Cells in SKG Mice. Scand J Immunol 87:28–35. doi:10.1111/sji.12626.
Engelmann R, Nekarda S, Kuthning D, Kneitz C, Müller-Hilke B. 2018. Decreased IgG4 ACPA levels in responders and increased CD1c+ classical dendritic cells in non-responders of patients with rheumatoid arthritis under therapy. Clin Rheumatol 37:1783–1790. doi:10.1007/s10067-018-4053-y.
Hartjen N, Bräuer L, Reiß B, Claassen H, Beileke S, Garreis F, Hoogeboom S, Tsokos M, Etzold S, Müller-Hilke B, Gelse K, Müller T, Goldring MB, Paulsen F, Schicht M. 2018. Evaluation of surfactant proteins A, B, C, and D in articular cartilage, synovial membrane and synovial fluid of healthy as well as patients with osteoarthritis and rheumatoid arthritis. PLoS One 13:e0203502. doi:10.1371/journal.pone.0203502.
Hollinski R, Osterberg A, Polei S, Lindner T, Cantré D, Mittlmeier T, Vollmar B, Bruhn S, Müller-Hilke B. 2018. Young and healthy C57BL/6 J mice performing sprint interval training reveal gender- and site-specific changes to the cortical bone. Sci Rep 8:1529. doi:10.1038/s41598-018-19547-z.
Klopsch C, Skorska A, Ludwig M, Lemcke H, Maass G, Gaebel R, Beyer M, Lux C, Toelk A, Müller K, Maschmeier C, Rohde S, Mela P, Müller-Hilke B, Jockenhoevel S, Vollmar B, Jaster R, David R, Steinhoff G. 2018. Intramyocardial angiogenetic stem cells and epicardial erythropoietin save the acute ischemic heart. Dis Model Mech 11. doi:10.1242/dmm.033282.
Kriebel K, Hieke C, Engelmann R, Potempa J, Müller-Hilke B, Lang H, Kreikemeyer B. 2018. Porphyromonas gingivalis Peptidyl Arginine Deiminase Can Modulate Neutrophil Activity via Infection of Human Dental Stem Cells. J Innate Immun 10:264–278. doi:10.1159/000489020.
Kriebel K, Hieke C, Müller-Hilke B, Nakata M, Kreikemeyer B. 2018. Oral Biofilms from Symbiotic to Pathogenic Interactions and Associated Disease -Connection of Periodontitis and Rheumatic Arthritis by Peptidylarginine Deiminase. Front Microbiol 9:53. doi:10.3389/fmicb.2018.00053.
Osterberg A, Engelmann R, Müller-Hilke B. 2018. Allogeneic yet major histocompatibility complex-matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced trabecular bone. J Bone Miner Metab 36:420–430. doi:10.1007/s00774-017-0859-y.
Engelmann R, Müller-Hilke B. 2017. Experimental silicosis does not aggravate collagen-induced arthritis in mice. J Negat Results Biomed 16:5. doi:10.1186/s12952-017-0071-6.
Fritzsche C, Ghanem H, Koball S, Mueller-Hilke B, Reisinger EC. 2017. High Pneumocystis jirovecii colonization rate among haemodialysis patients. Infect Dis (Lond) 49:132–136. doi:10.1080/23744235.2016.1225980.
Koenen K, Knepper I, Klodt M, Osterberg A, Stratos I, Mittlmeier T, Histing T, Menger MD, Vollmar B, Bruhn S, Müller-Hilke B. 2017. Sprint Interval Training Induces A Sexual Dimorphism but does not Improve Peak Bone Mass in Young and Healthy Mice. Sci Rep 7:44047. doi:10.1038/srep44047.
Koslowski N, Sombetzki M, Loebermann M, Engelmann R, Grabow N, Österreicher CH, Trauner M, Mueller-Hilke B, Reisinger EC. 2017. Single-sex infection with female Schistosoma mansoni cercariae mitigates hepatic fibrosis after secondary infection. PLoS Negl Trop Dis 11:e0005595. doi:10.1371/journal.pntd.0005595.
Neumann A-M, Abele J, Kirschstein T, Engelmann R, Sellmann T, Köhling R, Müller-Hilke B. 2017. Mycophenolate mofetil prevents the delayed T cell response after pilocarpine-induced status epilepticus in mice. PLoS One 12:e0187330. doi:10.1371/journal.pone.0187330.
Osterberg A, Thiem D, Herlyn P, Mittlmeier T, Frerich B, Müller-Hilke B. 2017. Subchondral bone sclerosis and cancellous bone loss following OA induction depend on the underlying bone phenotype. Joint Bone Spine 84:71–77. doi:10.1016/j.jbspin.2015.11.012.
Behrendt A-K, Kuhla A, Osterberg A, Polley C, Herlyn P, Fischer D-C, Scotland M, Wree A, Histing T, Menger MD, Müller-Hilke B, Mittlmeier T, Vollmar B. 2016. Dietary Restriction-Induced Alterations in Bone Phenotype: Effects of Lifelong Versus Short-Term Caloric Restriction on Femoral and Vertebral Bone in C57BL/6 Mice. J Bone Miner Res 31:852–863. doi:10.1002/jbmr.2745.
Borufka L, Volmer E, Müller S, Engelmann R, Nizze H, Ibrahim S, Jaster R. 2016. In vitro studies implicate an imbalanced activation of dendritic cells in the pathogenesis of murine autoimmune pancreatitis. Oncotarget 7:42963–42977. doi:10.18632/oncotarget.10265.
Engelmann R, Biemelt A, Cordshagen A, Johl A, Kuthning D, Müller-Hilke B. 2016. The Prerequisites for Central Tolerance Induction against Citrullinated Proteins in the Mouse. PLoS One 11:e0158773. doi:10.1371/journal.pone.0158773.
Hieke C, Kriebel K, Engelmann R, Müller-Hilke B, Lang H, Kreikemeyer B. 2016. Human dental stem cells suppress PMN activity after infection with the periodontopathogens Prevotella intermedia and Tannerella forsythia. Sci Rep 6:39096. doi:10.1038/srep39096.
Engelmann R, Wang N, Kneitz C, Müller-Hilke B. 2015. Bone resorption correlates with the frequency of CD5⁺ B cells in the blood of patients with rheumatoid arthritis. Rheumatology (Oxford) 54:545–553. doi:10.1093/rheumatology/keu351.
Meister S, Engelmann R, Kneitz C, Müller-Hilke B. 2015. The presence of FCGR2B promoter or transmembrane region variant alleles leads to reduced serum IL-6 levels in rheumatoid arthritis. Rheumatol Int 35:1311–1318. doi:10.1007/s00296-015-3226-0.
Sombetzki M, Fuchs CD, Fickert P, Österreicher CH, Mueller M, Claudel T, Loebermann M, Engelmann R, Langner C, Sahin E, Schwinge D, Guenther ND, Schramm C, Mueller-Hilke B, Reisinger EC, Trauner M. 2015. 24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis. J Hepatol 62:871–878. doi:10.1016/j.jhep.2014.11.020.
Fritzsche C, Riebold D, Fuehrer A, Mitzner A, Klammt S, Mueller-Hilke B, Reisinger EC. 2013. Pneumocystis jirovecii colonization among renal transplant recipients. Nephrology (Carlton) 18:382–387. doi:10.1111/nep.12054.
Pasold J, Engelmann R, Keller J, Joost S, Marshall RP, Frerich B, Müller-Hilke B. 2013. High bone mass in the STR/ort mouse results from increased bone formation and impaired bone resorption and is associated with extramedullary hematopoiesis. J Bone Miner Metab 31:71–81. doi:10.1007/s00774-012-0394-9.
Pasold J, Osterberg A, Peters K, Taipaleenmäki H, Säämänen A-M, Vollmar B, Müller-Hilke B. 2013. Reduced expression of Sfrp1 during chondrogenesis and in articular chondrocytes correlates with osteoarthritis in STR/ort mice. Exp Cell Res 319:649–659. doi:10.1016/j.yexcr.2012.12.012.
Salamon A, Jonitz-Heincke A, Adam S, Rychly J, Müller-Hilke B, Bader R, Lochner K, Peters K. 2013. Articular cartilage-derived cells hold a strong osteogenic differentiation potential in comparison to mesenchymal stem cells in vitro. Exp Cell Res 319:2856–2865. doi:10.1016/j.yexcr.2013.09.008.
Fitzner B, Müller S, Walther M, Fischer M, Engelmann R, Müller-Hilke B, Pützer BM, Kreutzer M, Nizze H, Jaster R. 2012. Senescence determines the fate of activated rat pancreatic stellate cells. J Cell Mol Med 16:2620–2630. doi:10.1111/j.1582-4934.2012.01573.x.
Hilgendorf I, Mueller-Hilke B, Kundt G, Holler E, Hoffmann P, Edinger M, Freund M, Wolff D. 2012. The lack of memory B cells including T cell independent IgM+ IgD+ memory B cells in chronic graft-versus host disease is associated with susceptibility to infection. Transpl Int 25:87–96. doi:10.1111/j.1432-2277.2011.01388.x.
Pohle D, Kasch R, Herlyn P, Bader R, Mittlmeier T, Pützer BM, Müller-Hilke B. 2012. Adenoviral transduction supports matrix expression of alginate cultured articular chondrocytes. Biotechnol Bioeng 109:2402–2408. doi:10.1002/bit.24505.
Arbeiten, die mit der Unterstützung der Core Facility entstanden sind:
Ehlers, Luise; Rohde, Sarah; Ibrahim, Saleh; Jaster, Robert (2018): Adoptive transfer of CD3+ T cells and CD4+ CD44high memory T cells induces autoimmune pancreatitis in MRL/MpJ mice. In: Journal of cellular and molecular medicine 22 (4), S. 2404–2412. DOI: 10.1111/jcmm.13537.
Eichhorst, Annika; Gallhof, Malte; Voss, Alice; Sekora, Anett; Eggers, Leon; Le Huyen, Thi et al. (2022): Spirooxindol-1,3-oxazine Alkaloids: Highly Potent and Selective Antitumor Agents Evolved from Iterative Structure Optimization. In: ChemMedChem 17 (14), e202200162. DOI: 10.1002/cmdc.202200162.
Feifei, Liu; Richter, Anna; Runge, Jens; Keiler, Jonas; Hermann, Andreas; Kipp, Markus; Joost, Sarah (2022): Spontaneous Hind Limb Paralysis Due to Acute Precursor B Cell Leukemia in RAG1-deficient Mice. In: Journal of molecular neuroscience : MN 72 (8), S. 1646–1655. DOI: 10.1007/s12031-022-02025-7.
Hecker, Michael; Fitzner, Brit; Putscher, Elena; Schwartz, Margit; Winkelmann, Alexander; Meister, Stefanie et al. (2022): Implication of genetic variants in primary microRNA processing sites in the risk of multiple sclerosis. In: EBioMedicine 80, S. 104052. DOI: 10.1016/j.ebiom.2022.104052.
Ibrahim, Badr; Stange, Jan; Dominik, Adrian; Sauer, Martin; Doss, Sandra; Eggert, Martin (2020): Albumin promotes proliferation of G1 arrested serum starved hepatocellular carcinoma cells. In: PeerJ 8, e8568. DOI: 10.7717/peerj.8568.
Klopsch, Christian; Skorska, Anna; Ludwig, Marion; Lemcke, Heiko; Maass, Gabriela; Gaebel, Ralf et al. (2018): Intramyocardial angiogenetic stem cells and epicardial erythropoietin save the acute ischemic heart. In: Disease models & mechanisms 11 (6). DOI: 10.1242/dmm.033282.
Ma, Yixuan; Sender, Sina; Sekora, Anett; Kong, Weibo; Bauer, Peter; Ameziane, Najim et al. (2022): Inhibitory Response to CK II Inhibitor Silmitasertib and CDKs Inhibitor Dinaciclib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines. In: International journal of molecular sciences 23 (8). DOI: 10.3390/ijms23084409.
Ma, Yixuan; Sender, Sina; Sekora, Anett; Kong, Weibo; Bauer, Peter; Ameziane, Najim et al. (2022): The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines. In: International journal of molecular sciences 23 (8). DOI: 10.3390/ijms23084295.
Putscher, Elena; Hecker, Michael; Fitzner, Brit; Boxberger, Nina; Schwartz, Margit; Koczan, Dirk et al. (2022): Genetic risk variants for multiple sclerosis are linked to differences in alternative pre-mRNA splicing. In: Frontiers in immunology 13, S. 931831. DOI: 10.3389/fimmu.2022.931831.
Salewski, Inken; Henne, Julia; Engster, Leonie; Schneider, Bjoern; Lemcke, Heiko; Skorska, Anna et al. (2021): Combined Gemcitabine and Immune-Checkpoint Inhibition Conquers Anti-PD-L1 Resistance in Low-Immunogenic Mismatch Repair-Deficient Tumors. In: International journal of molecular sciences 22 (11). DOI: 10.3390/ijms22115990.
Salewski, Inken; Henne, Julia; Engster, Leonie; Krone, Paula; Schneider, Bjoern; Redwanz, Caterina et al. (2022): CDK4/6 blockade provides an alternative approach for treatment of mismatch-repair deficient tumors. In: Oncoimmunology 11 (1), S. 2094583. DOI: 10.1080/2162402X.2022.2094583.
Sombetzki, Martina; Koslowski, Nicole; Rabes, Anne; Seneberg, Sonja; Winkelmann, Franziska; Fritzsche, Carlos et al. (2018): Host Defense Versus Immunosuppression: Unisexual Infection With Male or Female Schistosoma mansoni Differentially Impacts the Immune Response Against Invading Cercariae. In: Frontiers in immunology 9, S. 861. DOI: 10.3389/fimmu.2018.00861.
Sombetzki, Martina; Rabes, Anne; Bischofsberger, Miriam; Winkelmann, Franziska; Koslowski, Nicole; Schulz, Cindy; Reisinger, Emil C. (2019): Preventive CTLA-4-Ig Treatment Reduces Hepatic Egg Load and Hepatic Fibrosis in Schistosoma mansoni-Infected Mice. In: BioMed research international 2019, S. 1704238. DOI: 10.1155/2019/1704238.
Thamilarasan, Madhan; Hecker, Michael; Goertsches, Robert Hermann; Paap, Brigitte Katrin; Schröder, Ina; Koczan, Dirk et al. (2013): Glatiramer acetate treatment effects on gene expression in monocytes of multiple sclerosis patients. In: Journal of neuroinflammation 10, S. 126. DOI: 10.1186/1742-2094-10-126.
Völkner, Christin; Peter, Franziska; Liedtke, Maik; Krohn, Saskia; Lindner, Iris; Murua Escobar, Hugo et al. (2019): Generation of the Niemann-Pick type C2 patient-derived iPSC line AKOSi001-A. In: Stem cell research 41, S. 101606. DOI: 10.1016/j.scr.2019.101606.